3 Examples of POCT Microfluidics

release time:2022-05-31 11:41:32

In recent years, the rapid development of microfluidics in the medical industry has attracted more and more attention. Microfluidics is a technology of microfluidic system with functions and specific tasks consisting of microchannels and microstructures. It combines the essential functions of multiple disciplines such as biology, chemistry, medicine and electronics, such as sample preparation, reaction and fractionation. The fractionation and detection technology is a miniaturized technology that is widely used in chemical analysis, genetic analysis, biomedicine, chemical synthesis, and nanomaterial preparation.

Microfluidics offers absolute advantages in terms of fractionation and time for chemical and biological analysis. It enables high precision and sensitive separation and detection even with little sample and reagents. It has low cost, short analysis time, small analytical equipment imprint, small size, good microchannel fluid characteristics, and microfluidics has had a great impact on Point of care technology (POCT).

POCT microfluidic nucleic acid testing

Deoxyribonucleic acid, or DNA, is the primary substance for replication, storage and transmission of information. Therefore, there are specific requirements for the environment underlying nucleic acid testing. Nucleic acid testing includes pre-processing, nucleic acid amplification and identification of amplicon components. This makes the assay process complex, with long run times and high reagent costs.

With the advancement of technology, the research team has been able to simplify the complex process through microfluidic technology and concentrate it on a smaller chip. This largely shortens the testing cycle and saves the cost of testing and time, thus improving the high precision and sensitivity of the nucleic acid test.

POCT microfluidic chip for blood glucose testing

POCT chip shows its great role in the diagnosis of endocrine diseases. Blood glucose meter is the most common immediate diagnostic device. It detects the glucose level in the blood through a very small amount of blood, easy to operate, low reagent dosage, small test marks and short time. Glucose meters are a major step towards personal health management and have become a benchmark test in the field of clinical glucose testing.

POCT microfluidic chip cardiac marker test

Using the principle of immunoassay, a rapid immune reaction is accomplished by controlling the fluid and antigen-antibody reaction through microfluidic channels on the chip. This method is characterized by low reagent consumption, short analysis time, ease of integration, and automation. This largely reduces the need for operators and enables the development of simple and convenient medical devices.

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